Science Editorial
CONNECTING THE HIDDEN DOTS BETWEEN TOXINS AND ENDOCRINE HEALTH
One of the most striking innovations emerging from this collaboration is the identification of what Dr. Bard cleverly calls the “Starry Night” signature—an ultrasound pattern that visually captures early inflammatory or autoimmune activity in tissue. For integrative clinicians, this is an invaluable diagnostic cue, providing confirmation that cellular and metabolic disturbances are not just theoretical—they are visible. It validates what functional medicine has long proposed: that toxins and oxidative stress create micro-inflammatory cascades long before full-blown disease develops.HEAVY METAL EXPOSURE can leave visible clues on the body’s surface—particularly through changes in skin color, texture, and resilience. In functional and environmental medicine, these external signs often serve as the first indicators of deeper biochemical disturbances. Below is a breakdown of three common dermatologic responses linked to toxic metal exposure, each reflecting a distinct underlying mechanism.
Hyperpigmentation
Hyperpigmentation refers to darkened patches or spots on the skin caused by excess melanin production. In cases of heavy metal exposure—particularly arsenic—melanin synthesis can become overstimulated as the body reacts to oxidative stress and cellular injury. The result is a pattern of grayish-brown or black discoloration, sometimes described as a “raindrop” appearance on the trunk, neck, or extremities. Lead exposure may also contribute by altering enzyme activity in melanocytes, the pigment-producing cells, resulting in uneven or mottled skin tone.
Hypopigmentation
Hypopigmentation is the opposite effect—the loss or reduction of normal skin color due to diminished melanin production or destruction of melanocytes. Chronic exposure to arsenic or mercury can damage the pigment cells themselves or disrupt the pathways that regulate melanin synthesis. This produces irregular pale patches, often interspersed with darker areas, giving the skin a patchy or marbled appearance. The contrast between hyper- and hypopigmented zones can sometimes be an early dermatologic sign of cumulative toxic stress.
Hyperkeratosis
Hyperkeratosis involves an abnormal thickening of the outer skin layer, the stratum corneum, due to accelerated production of keratin. In arsenic-related cases, this hardening typically appears on the palms and soles, where small, corn-like elevations develop over time. These lesions may evolve into painful nodules or fissures if exposure continues. The thickened skin represents the body’s attempt to protect itself from ongoing irritation or injury at the cellular level—a defensive, yet maladaptive, reaction to chronic toxicity.
Together, these manifestations—hyperpigmentation, hypopigmentation, and hyperkeratosis—offer valuable diagnostic insight. They are the skin’s visual language for what is happening beneath the surface: the cumulative stress of heavy metals like arsenic, lead, and mercury altering cellular metabolism, hormone regulation, and immune signaling long before systemic disease is diagnosed.
This **two-step model—screening and confirming—**represents the future of precision endocrinology. By integrating toxin mapping through OligoScan with high-resolution ultrasound, practitioners can track how detoxification, chelation, or mineral rebalancing therapies are truly influencing patient physiology. It transforms the process from guesswork into measurable, visual progress.
In a world where environmental exposures are rising, this partnership between toxin science and endocrine diagnostics offers hope—and a clear path toward early intervention and true functional restoration.
AUTHOR:
Angela Mazza, DO is a triple board-certified endocrinologist specializing in thyroid and hormone health. Her expertise is essential to LYMESCAN’s multidisciplinary care, as Lyme disease often disrupts endocrine function, mimicking or triggering conditions like Hashimoto’s thyroiditis. Dr. Mazza’s precision in evaluating thyroid dysfunction helps distinguish infectious causes from autoimmune disorders, providing patients with targeted, hormone-balanced recovery plans.
Tech Perspective:
THE UNSEEN REACTIONS OF MODERN MEDICINE
By Dr. Robert L. Bard, Diagnostic Imaging Specialist
For much of my own career, I have worked as both a clinician and an investigator—bridging imaging science with human experience. Through my Second Opinion Scan Program, I have evaluated countless patients whose symptoms defied traditional medical categories. These were individuals who had seen multiple specialists, endured years of lab work and inconclusive scans, only to be told that “nothing is wrong.” Yet, using advanced ultrasound, Doppler imaging, and thermography, we often discovered subtle inflammatory patterns, lymphatic stagnation, or vascular disturbances—markers of biological stress that conventional protocols overlooked. In some, the cause traced back to hidden infections; in others, to adverse reactions from metal implants or amalgams, eerily similar to the case Dr. Blodgett described.
Throughout history, medicine has repeatedly learned this lesson: our technologies evolve faster than our wisdom to interpret their impact. From the first amalgam fillings in the 1800s to the widespread use of titanium implants and orthopedic hardware, metals have been heralded as durable solutions—but seldom scrutinized for individual biocompatibility. Now, with modern tools like OligoScan, we can measure heavy metal accumulation in tissues in real time through noninvasive spectrophotometry. This technology provides a rapid window into intracellular mineral and toxic metal levels—offering clinicians a valuable baseline for detoxification and early intervention. (More features on the OligoScan )
Our partnership with Dr. Scott Schroeder and his metal sensitivity awareness mission continues to reveal that patients affected by aluminum, nickel, or titanium exposure often experience systemic symptoms: chronic fatigue, neuropathy, cognitive fog, joint pain, and, in severe cases, depression or suicidal ideation. These are not isolated psychosomatic reactions—they are physiological responses to immune dysregulation and neurotoxicity. As imaging specialists, we are now documenting patterns of localized inflammation, lymphatic compromise, and microcirculatory disruption around implant sites, findings that correlate strongly with patient-reported distress.
Today’s frontier in integrative diagnostics demands that we move beyond the narrow definitions of “normal.” The union of biological scanning tools like OligoScan with imaging modalities such as ultrasound and thermology offers a new path to visualize and validate what patients have always known about their own bodies. In that convergence lies both scientific evolution and human redemption—a medicine that listens, sees, and finally believes the patient.
When Elevated Metals Show Up, Don’t Panic—Get Curious
Discovering elevated metal levels in your body can be unsettling, but the first rule is simple: don’t panic. Metal toxicity is not a sentence—it’s a signal. The body is remarkably capable of recovery when the source of exposure is identified and addressed intelligently. The key is to step back, think critically, and investigate where these metals might be coming from.
When my OligoScan results first indicated an unusually high level of mercury, I confirmed it with a follow-up blood test, which yielded the same finding. As a physician and imaging researcher, I wasn’t shocked—but I was deeply curious. I eat fish roughly four times a week, often tuna and swordfish, both known to carry high mercury content. That explained part of the story. But digging deeper, I recalled that during my military service, mercury exposure was far more insidious: it was in fluorescent light tube disposal, broken thermometers, munitions maintenance, dental amalgams, and even older disinfectant compounds used in the field. Like many veterans, I had carried this invisible legacy for decades without realizing it.
The lesson is this: when metals show up, look first at environmental, occupational, and lifestyle sources. Mercury can enter the body through seafood, contaminated water, certain cosmetics, dental fillings, and industrial emissions. Lead might stem from old plumbing, paint, or solder. Aluminum appears in cookware, deodorants, and pharmaceuticals. Identifying your exposure sources allows you to act strategically instead of emotionally.
Once identified, detoxification becomes a process of gradual, guided correction—not an emergency purge. Medical supervision is critical, especially when metal levels are high. Common interventions include:
Chelation therapy using agents like DMSA or EDTA, under physician oversight, to bind and eliminate metals.
Nutritional detoxification, emphasizing antioxidants (vitamin C, selenium, alpha-lipoic acid, glutathione) to support liver and kidney clearance.
- Sweat-based therapies such as infrared sauna and PEMF-assisted circulation to promote toxin elimination through the skin.
Mineral rebalancing, since heavy metals often displace essential minerals like zinc, magnesium, and selenium.
Dietary adjustments, reducing high-mercury fish and increasing plant-based foods that naturally bind metals, such as cilantro, chlorella, and garlic.
Above all, document your progress. Follow-up scans, like OligoScan, can reveal real-time improvements as your body restores equilibrium. The goal isn’t perfection—it’s awareness. Every data point tells a story about where you’ve been, what you’ve absorbed, and how your body is reclaiming its balance. Elevated metals are not just lab numbers; they’re a message urging you to live and heal more consciously.
A Path Back to Balance: True detoxification is not a race—it’s a guided return to balance. Under proper physician supervision, chelation therapy with agents like DMSA or EDTA can safely bind and remove toxic metals, while nutritional support with antioxidants such as vitamin C, selenium, alpha-lipoic acid, and glutathione strengthens the body’s natural detox systems. Sweat-based therapies like infrared sauna and PEMF enhance circulation and accelerate elimination through the skin, while mineral rebalancing restores essential nutrients displaced by toxins. Finally, mindful dietary choices—reducing high-mercury fish and increasing detox-supportive foods like cilantro, chlorella, and garlic—complete the process. Each of these measures works synergistically, forming a restorative blueprint that helps the body cleanse, replenish, and reclaim its equilibrium with intelligence rather than urgency.
Feature Story
Dr. Blodgett’s collaboration with orthopedic surgeon Dr. Scott Schroeder, a fellow pioneer in exploring metal sensitivity and implant safety, represents a critical intersection of two fields—dentistry and orthopedic medicine—both reckoning with the unintended consequences of metallic biocompatibility. Together, they are expanding the conversation about toxic load, immune disruption, and the mental and emotional toll of metal allergies, moving modern care toward compassion, caution, and science-driven awareness.
In his Portland-based clinic, Mondays are reserved solely for meeting new patients. These appointments are not rushed. They are immersive conversations that explore “the risks presented in their mouths and the rest of their body,” from metal implants to jaw infections. His holistic model rejects the profit-driven “supervised neglect” of conventional dentistry and replaces it with deliberate, measured, and biologically mindful care.
From that day forward, he abandoned titanium implants entirely, replacing them with safer biocompatible ceramics and offering pre-procedure testing through platforms like BioComp Laboratories and the MELISA test. His diligence ensures that every restorative choice considers the patient’s biology. “Once you learn something, you can’t unlearn it,” he says—a mantra that defines his medical integrity.
Equally revolutionary is his incorporation of acupuncture meridian assessment to evaluate energetic imbalances, along with tools like InBody scanning, PEMF therapy, and full-body infrared light systems. These modalities, once dismissed by mainstream dentistry, are now integral to his “wellness wing”—a thousand-square-foot extension of his clinic where biological restoration and energy recalibration converge.
His use of social media, particularly Instagram, has become an unexpected global platform for change. What began as a reluctant experiment eight years ago evolved into an international educational network. Each post features real patient stories, detailed visuals, and PubMed-supported findings, allowing thousands worldwide to access knowledge often hidden behind professional barriers. “I get messages every day from people in India or Libya who found hope through a story I shared,” he says with humility. For many, his digital storytelling has become a lifeline toward understanding invisible illness and the link between oral and systemic health.
Through platforms like Dr. Schroeder’s DetoxScan initiative and collaborations with integrative physicians, Dr. Blodgett extends his mission beyond Portland to a national dialogue on metal safety, mental health, and biological restoration. Together, they are changing the very definition of what it means to practice medicine with conscience.
As Dr. Blodgett reflects, “It’s always nice to grow the fraternity of people who want to carry the torch for better choices and better awareness.” In partnership with pioneers like Dr. Schroeder, he is not just changing smiles—he is changing lives, one mindful restoration at a time.
Part 3: Science News
Disclaimer: The information provided on this page is for educational and informational purposes only and is not intended as a substitute for professional medical advice, diagnosis, or treatment. Always seek the advice of your physician or other qualified healthcare provider with any questions you may have regarding a medical condition, exposure concern, or before starting any new health regimen. Never disregard professional medical advice or delay seeking it because of information you have read here.
Exploring High Mercury content
Mercury is a naturally occurring element found in air, water, and soil—but when it enters the human body, even in small amounts, it can cause serious harm. “Elevated mercury” refers to higher-than-normal levels detected in the blood, urine, or hair—an indicator of toxic exposure. The degree of elevation often reveals how, and how long, someone has been exposed.
At the mildest end, mercury levels may rise from frequent consumption of high-mercury fish such as tuna, swordfish, mackerel, or shark. These exposures are usually dietary and gradual, affecting individuals who eat fish several times per week. Mercury from fish (methylmercury) is highly absorbable and accumulates in tissues, particularly in the brain and kidneys, potentially causing fatigue, brain fog, tingling, or mood changes.
More moderate exposure may stem from dental amalgams (“silver fillings”), broken thermometers, fluorescent bulbs, or industrial pollution. Inhalation of mercury vapors during home renovations or lab work can raise internal levels quickly. Pregnant women, children, and those with compromised detoxification capacity (such as certain genetic polymorphisms) are especially at risk.
The most severe cases appear in military or occupational settings. Service members, miners, welders, factory workers, and demolition specialists may inhale inorganic mercury dust or vaporized metal through repeated contact with ammunition, electronic components, or chemical solvents. In these cases, mercury can damage the nervous system, endocrine glands, and cardiovascular system, mimicking other chronic illnesses.
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Mitigation and Recovery
Reducing exposure is the first step—limit high-mercury fish, replace old dental amalgams safely (by a biologic dentist), and ensure proper ventilation in industrial or laboratory environments. Testing through urine, blood, or OligoScan technology helps identify body burden.
Medical management often involves detoxification under professional supervision. Functional or integrative physicians, environmental medicine specialists, and endocrinologists are well-equipped to assess systemic impact—especially on thyroid, adrenal, and reproductive hormones, which mercury can disrupt.
Supplemental support may include:
Selenium, which binds mercury and protects cells.
Alpha-lipoic acid (ALA) and N-acetyl cysteine (NAC), supporting liver detox pathways.
Glutathione, the body’s master antioxidant.
Chlorella and spirulina, natural chelators that bind heavy metals.
For advanced cases, supervised chelation therapy (e.g., with DMSA or DMPS) may be considered, though it must be carefully monitored.
Ultimately, elevated mercury is both a warning and an opportunity—to identify toxic exposure early, restore balance through guided detox, and protect the body from long-term neurological and endocrine damage.
References
(1) Agency for Toxic Substances and Disease Registry. (2021). Toxicological profile for mercury. U.S. Department of Health and Human Services. https://www.atsdr.cdc.gov/toxprofiles/tp46.pdf (2) Clarkson, T. W., Magos, L., & Myers, G. J. (2003). The toxicology of mercury—Current exposures and clinical manifestations. New England Journal of Medicine, 349(18), 1731–1737. https://doi.org/10.1056/NEJMra022471 (3) U.S. Environmental Protection Agency. (2023). Fish and shellfish advisories and safe eating guidelines. https://www.epa.gov/choose-fish-and-shellfish-wisely (4) Mutter, J., Naumann, J., Sadaghiani, C., Schneider, R., & Walach, H. (2004). Amalgam studies: Disregarding basic principles of mercury toxicity. International Journal of Hygiene and Environmental Health, 207(4), 391–397. https://doi.org/10.1078/1438-4639-00293 (5) Houston, M. C. (2011). The role of mercury and cadmium heavy metals in vascular disease, hypertension, coronary heart disease, and myocardial infarction. Alternative Therapies in Health and Medicine, 17(2), 64–69.
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